Mezcal Vs. Tequila: Understanding the Key Differences

When to use mezcal or tequila? Since mezcal and tequila are both made from agave, they work well in similar drinks. [Ilegal Global Brand Ambassador Gilbert] Marquez uses the mantra, “if it grows together, it goes together.”

“For me, flavors that are endemic to Mexico will always pair well with mezcal or tequila,” he says. Flavors like citrus, agave nectar, and peppers pair well with both liquors. You also can’t go wrong with salt and lime.

Since mezcal has a smokier flavor, it can add depth to cocktails typically associated with tequila, like a margarita or paloma.